Burkhard Pleger_____________________

 

Burkhard Pleger, MD

neurologist

medical computer scientist

date of birth: 15.07.70

place of birth: Münster (Westfalen), Germany

Max Planck Institute for Human Cognitive and Brain Sciences
Stephanstraße 1a; 04103 Leipzig, Germany
P.O. box 500355; 04303 Leipzig, Germany
Phone: +49 (0) 341-9940-135
Fax: +49 (0) 341-9940-2221

 List of publications:

2000
2001
2003
2004
2005
2006
2007
2008
2009
2010

2000

1. Ossege LM, Postler E, Pleger B, Muller KM, Malin JP (2000) Neoplastic cells in the cerebrospinal fluid in intravascular lymphomatosis. J. Neurol. 247: 656-658

 

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2001

2. Pleger B, Dinse HR, Ragert P, Schwenkreis P, Malin JP, Tegenthoff M (2001) Shifts in cortical representations predict human discrimination improvement. Proc. Natl. Acad. Sci. U S A 98: 12255-12260

 

3. Pleger B, Beyer HK, Laufer U (2001) Detection of liver lesions: magnetic resonance tomography using superparamagnetic iron particles (AMI-25, endorem) as a contrast medium in comparison with ultrasound diagnosis, computerized tomography and CT portography. Röntgenpraxis 53: 245-249

 

4. Schwenkreis P, Pleger B, Höffken O, Malin JP, Tegenthoff M (2001) Repetitive training of a synchronised movement induces short-term plastic changes in the human primary somatosensory cortex. Neurosci. Lett. 312: 99-102

 

5. Schwenkreis P, Witscher K, Janssen F, Pleger B, Dertwinkel R, Zenz M, Malin JP, Tegenthoff M (2001) Assessment of reorganization in the sensorimotor cortex after upper limb amputation. Clin. Neurophysiol. 112: 627-635

 

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2003

6. Pleger B, Schwenkreis P, Dinse HR, Ragert P, Höffken O, Malin JP, Tegenthoff M (2003) Pharmacological suppression of plastic changes in human primary somatosensory cortex after motor learning. Exp. Brain. Res. 148: 525-532

 

7. Pleger B, Förster AF, Widdig W, Henschel M, Nicolas V, Jansen A, Frank A, Knecht S, Schwenkreis P, Tegenthoff M (2003) Functional magnetic resonance imaging mirrors recovery of visual perception after repetitive tachistoscopic stimulation in patients with partial cortical blindness. Neurosci. Lett. 335: 192-196

 

8. Dinse HR, Ragert P, Pleger B, Schwenkreis P, Tegenthoff M (2003) Pharmacological modulation of perceptual learning and associated cortical reorganization. Science 301: 91-94

 

9. Ragert P, Dinse HR, Pleger B, Wilimzig C, Frombach E, Schwenkreis P, Tegenthoff M (2003) Combination of 5 Hz repetitive transcranial magnetic stimulation (rTMS) and tactile coactivation boosts tactile discrimination in humans. Neurosci. Lett. 348: 105-108

 

10. Schwenkreis P, Pleger B, Cornelius B, Weyen U, Dertwinkel R, Zenz M, Malin JP, Tegenthoff M (2003) Reorganization in the ipsilateral motor cortex of patients with lower limb amputation. Neurosci. Lett. 349: 187-190

 

11. Schwenkreis P, Janssen F, Rommel O, Pleger B, Völker B, Hosbach I, Dertwinkel R, Maier C, Tegenthoff M (2003) Bilateral motor cortex disinhibition in complex regional pain syndrome (CRPS) type I of the hand. Neurology 61: 515-519

 

12. Schwenkreis P, Maier C, Pleger B, Mansourian N, Dertwinkel R, Malin JP, Tegenthoff M, Zenz M (2003) NMDA-mediated mechanisms in cortical excitability changes after limb amputation. Acta. Neurol. Scand. 108: 179-184

 

13. Pleger B, Foerster A-F, Ragert P, Dinse HR, Schwenkreis P, Malin JP, Nicolas V, Tegenthoff M (2003) Functional imaging of perceptual learning in human primary and secondary somatosensory cortex. Neuron 40: 643-653

 

14. Dinse HR, Ragert P, Pleger B, Schwenkreis P, Tegenthoff M (2003) GABAergic mechanisms gate tactile discrimination learning. Neuroreport 14: 1747-1751

 

15. Widdig W, Pleger B, Rommel O, Malin, JP, Tegenthoff M (2003) Repetitive visual stimulation: a neurophysiological approach to the treatment of cortical blindness. NeuroRehabilitation 18: 227-237

 

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2004

16. Ragert P, Becker M, Tegenthoff M, Pleger B, Dinse HR (2004) Sustained increase of somatosensory cortex excitability by 5 Hz repetitive transcranial magnetic stimulation studied by paired madian nerve stimulation in humans. Neurosci. Lett. 356(2): 91-94, pdf

 

17. Pleger B, Janssen F, Schwenkreis P, Völker B, Maier C, Tegenthoff M (2004) Repetitive transcranial stimulation of the motor cortex attenuates pain perception in complex regional pain syndrome type I. Neurosci. Lett. 356(2): 87-90, pdf

 

18. Pleger B, Tegenthoff M, Schwenkreis P, Janssen F, Ragert P, Dinse HR, Völker B, Zenz M, Maier C (2004) Mean sustained pain levels are linked to hemispherical side-to-side differences of primary somatosensory cortex in the complex regional pain syndrome I. Exp. Brain Res. 155: 115-119, pdf 

 

19. Pleger B, Foerster A-F, Schwenkreis P, Nicolas V, Malin JP, Frettloeh J, Maier C, Tegenthoff M (2004) Untersuchung von Visusstörungen beim Tolosa-Hunt-Syndrom mittels der funktionellen Magnetresonanztomographie zur Abgrenzung psychogener Störungen - ein Fallbericht [Functional imaging of the visual cortex in the tolosa-hunt-syndrome for the detection of a psychogenic disorder - a case-report]. Schmerz 18 (3):211-217

 

20. Tegenthoff M, Cornelius B, Pleger B, Malin JP, Schwenkreis P (2004) Amphetamine enhances training-induced motor cortex plasticity. Acta Neurol. Scand. 109 (5):330-336, pdf

 

21. Pleger B, Schwenkreis P, Grünberg C, Malin JP, Tegenthoff M (2004) Fluoxetine facilitates use-dependent excitability of human primary motor cortex. Clin. Neurophysiol. 115:2157-2163, pdf

 

22. Drager B, Jansen A, Bruchmann S, Forster AF, Pleger B, Zwitserlood P, Knecht S (2004) How does the brain accommodate to increased task difficulty in word finding? A functional MRI study. NeuroImage. 23(3):1152-60, pdf  

 

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2005

23. Pleger B, Tegenthoff M, Ragert P, Förster AF, Dinse H, Schwenkreis P, Nicolas V, Maier C (2005) Sensorimotor retuning in compex regional pain syndrome parallels pain reduction. Ann Neurol. 57:425-429, pdf

 

24. Pleger B, Tegenthoff M, Dinse HR, Ragert P, Schwenkreis P (2005) Pharmacology of motor and somatosensory skills in humans. Curr. Neuropharmacology. 3:145-156, Review 

 

25. Dinse HR, Kalisch T, Ragert P, Pleger B, Schwenkreis P, Tegenthoff M (2005) Improving human haptic performance in normal and impaired human populations through unattended activation-based learning. Transactions on Applied Perception. 2:71-88, Review

 

26. Schwenkreis P, Witscher K, Pleger B, Malin JP, Tegenthoff M (2005) The NMDA antagonist memantine affects training induced motor cortex plasticity - a study using transcranial magnetic stimulation. BMC Neurosci. 6(1):35, pdf

 

27. Tegenthoff M, Ragert P, Pleger B, Schwenkreis P, Förster AF, Nicolas V, Dinse HR (2005) Improvement of tactile performance and enlargement of cortical somatosensory maps after 5 Hz rTMS. PLoS Biol. 3(11):e362, pdf

 

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2006

28. Pleger B, Ragert P (2006) Pharmacological support of Neurorehabilitation. Curr. Drug Therapy. 1:17-22, Review

 

29. Pleger B, Blankenburg F, Bestmann S, Ruff C, Wiech K, Stephan KE, Friston K, Dolan R (2006) Repetitive transcranial magnetic stimulation-induced changes in sensorimotor coupling parallel improvements of somatosensation in humans. J. Neurosci. 26(7):1945-52, pdf

 

30. Pleger B, Ragert P, Schwenkreis P, Forster A-F, Wilimzig C, Dinse H, Nicolas V, Maier C, Tegenthoff M (2006) Patterns of cortical reorganization parallel impaired tactile discrimination and pain intensity in Complex Regional Pain Syndrome. NeuroImage. 32(2): 502-510, pdf

 

31.Pleger B, Ruff C, Blankenburg F, Bestmann S, Wiech K, Stephan KE, Capilla A, Friston K, Dolan R (2006) Neural encoding of tactile decisions in human prefrontal cortex. J. Neurosci. 26(48):12596-12601, pdf

 

32. Wiech K, Kalisch R, Weiskopf N, Pleger B, Stephan KE, Dolan RJ (2006) Anterolateral prefrontal cortex mediates the analgesic effect of expected and perceived control over pain. J. Neurosci. 26(44):11501-11509, pdf

 

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2007

33. Schwenkreis P, El Tom S, Ragert P, Pleger B, Tegenthoff M, Dinse HR (2007) Assessment of sensorimotor cortical representation asymmetries and motor skills in violoine players. Eur. J. Neurosci. 26(11):3291-3302, pdf

 

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2008

34. Pleger B, Blankenburg F, Ruff C, Driver J, Dolan R (2008) Reward facilitates tactile judgments and modulates hemodynamic responses in human primary somatosensory cortex. J. Neurosci. 28(33):8161-8168-12601, pdf

 

35. Petrovic P, Pleger B, Seymour B, Klöppel S, De Martino B, Critchley H, Dolan R (2008) Blocking central opiate function modulates hedonic impact and anterior cingulate response to rewards and losses. J. Neurosci. 28(42):10509-10516, pdf

 

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2009

36. Lissek S, Wilimzig C, Stude P, Pleger B, Kalisch T, Maier C, Peters SA, Nicolas V, Tegenthoff M, Dinse HR (2009) Immobilization Impairs Tactile Perception and Shrinks Somatosensory Cortical Maps. Curr. Biol. 19(10):837-42, pdf

 

37. Obermann M, Pleger B, de Greiff A, Stude P, Kaube H, Diener HC, Katsarava Z (2009) Temporal summation of trigeminal pain in human anterior cingulate cortex.. NeuroImage 46(1):193-200, pdf

 

38. Pleger B, Ruff CC, Blankenburg F, Klöppel S, Driver J, Dolan R (2009) Influence of Dopaminergically Mediated Reward on Somatosensory Decision-Making. PLoS. Biol. 7(7): e1000164, pdf

 

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2010

39. Schneider SA, Pleger B, Draganski B, Cordivari C, Rothwell JC, Bhatia KP, Dolan RJ (2010) Modulatory effects of 5Hz rTMS over the primary somatosensory cortex in focal dystonia-An fMRI-TMS study. Mov. Disord., pdf

 

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b.pleger´2009