a hierarchy of successively simpler Heinrich models

Heinrich's model may be simplified in stages while retaining the basic differentiation features:

  • variable compartment sizes can be replaced by constant sizes
  • the pairs of snares replaced by single self-complementary snares
  • the vesicles arising from each compartment no longer distinguished kinetically
  • the two compartments treated antisymmetrically.
  • In addition, we have investigated the influence of the fusion rate normalization on the properties of the model.


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